Adoodle’s NOXO division is focused to develop a variety of products, which may in the future modify behavior, via olfactory senses, such as smoking cessation or weight control, as examples. The company's first product to reach commercialization is called NOXO, which has the ability to alter the brains ability to smell horrific odors. The odor is still there and it's not masked. The brain does not however, register its normal reaction to it. The uniquely formulated NOXO is based on advanced olfactory perception altering technology developed by Dr. V Ruth Pinney who is a director of Adoodle and who also directs the research at the company's new research center in The Woodlands, Texas.
Dr. Pinney worked with the Department of Justice to commercialize this product in order to support the brave efforts of our military, first responders, and law enforcement personnel. The earlier, first-generation product has been used extensively around the world including NYFD and first responders after 9/11, Dover AFB, and after natural disasters resulting from tsunamis, earthquakes, and hurricanes. This technology and the new second-generation products have now found its way into the medical and dental arena.
Olfaction refers to the sense of smell. Specialized sensory cells of the nasal cavity mediate this sense. For humans, the olfactory system detects volatile chemicals. The chemicals themselves, which activate the olfactory system, generally at very low concentrations, are called odors. Humans respond to chemical stimuli in their environments through chemoreception processes. Chemoreception depends primarily on the senses of taste, smell and includes trigeminal nerve stimulation in the nasal area. Chemoreception relies on chemicals that act as signals to regulate cell function, without the chemical necessarily being taken into the cell for metabolic purposes. While many chemicals, hormones and neurotransmitters, occur within organisms and serve to regulate specific physiological activities, chemicals in the external environment are also perceived by and elicit responses. The company intends to complete the development of new products so that human behaviors can be modified by selectively inhibiting or changing chemo-perception or by causing a selected chemo-perceptions take place.
The company announced its new research facility. The research efforts conduct their focus on monetizable olfactory perception altering technologies. The NOXO Olfactory Research Laboratory is developing new and advanced products for the company, which may have a material effect on human biological functions and neurological systems responses.
HOW NOXO PRODUCTS WORK - THE SCIENCE OF NOXO
There are 12 “Major” terminal nerves in the body, all but one terminate in the brain stem. The one that doesn’t is the olfactory nerve that terminates just below the the frontal lobe on the bottom side of the brain near both the brain interior and tangential to the lower frontal cortex (the frontal cortex being the major cognitive center of the brain). See diagram. The olfactory bulb is in red:
No one really knows why this nerve terminates here and not where the other 11 nerves do. However because it is where it’s located, it has access to several other areas including the limbic system which is the emotional center of the brain.
From its location, the olfactory bulb receives input from the olfactory nerves and transmits smell information from the nose to the brain. By observing it “work” under an fMRI, we’ve learned that this center not only transmits data to the brain but specifically receives it from other “interior” brain areas such as the hippocampus and amygdala as well as from our “thinking” neocortex. With this in mind, the center receives both emotional and thinking messages.
Summing it up its functions appear to be that of “enhancing discrimination between different smells” as well as filtering out many odors to permit the transmission of specific ones. The fact that it permits the “cognitive or thinking” brain areas to participate, even to modify the detection and discrimination of odors is what makes NOXO's work, operable.
The Olfactory Bulb is only part of the entire Olfactory or smell system as you can see in the diagram below:
Nerve cell extensions (axons) from the olfactory system converge in the bulb where other cells (mitral cells) send their axons or extensions of themselves into a number of brain areas including the medial amygdala and the entorhinal cortex.
Within the central nervous system, odors are seen as “patterns of neuronal activity” and may be encoded by other sensory areas including the area of the brain responsible for interpreting sound patterns. Notice how close for example the highly cognitive prefrontal cortex is to the olfactory bulbs. On an fMRI, it is obvious that they communicate. Also notice how close the Temporal Lobes (areas in green) are to the olfactory system. The Temporal Cortex (working in conjunction with the limbic system [emotional center]) is responsible for the formation of our memories.
Below is a diagram of the Brain’s Listening/Hearing Center. Notice it’s proximity to the Temporal lobes and that it lies adjacent to the brain’s interior limbic system:
MUSIC, unlike any other stimulus is a whole brain activity. When you or I listen to music, every single part of our brain picks up the stimulus and engages in its processing.
THEREFORE, even the brains olfactory system is involved in music processing.
Because our smell center is “set” off by itself near the emotional and thinking centers of the brain, smells can generate memories and specifically “memories of sounds.” FOR EXAMPLE: a thought of Sunday Morning breakfasts cooked by our grandmother conjures up images of tastes (for me biscuits and redeye gravy, etc.); visuals (my grandmother baking) and sounds (specifically music that she would have on the radio, usually religious songs from Sunday services.
That NOXO uses memories of sounds (which is really what we are talking about) to engage the brain’s other systems is not all that surprising. NOXO knows that its’ our brain’s listening system that processes sound, but we refer to the thinking part of the brain (the cerebral cortex) a perceiving and processing our “musical” sounds.
Admittedly, one must know a great deal about the brain to understand what NOXO science is talking about and physicians do tend not to understand this area as well as neuroscientists.
When NOXO talks about “tricking” the cortical areas, it's true. The smells are being processed, but it’s the other brain areas that are being bamboozled into perceiving something other than what is real.
So this is what we focus on when doing research relating to present and future products.
NOXO Odor Inhibitor
New NOXO Odor Inhibitor balm, secret proprietary product formula of 14 special ingredients which blocks nauseating and offensive odors when applied topically, under the nostrils.
NOXO Smoking Control
New NOXO Smoking Control balm, when applied topically, under the nostrils reduces an abstaining tobacco user's urge to smoke. The scent of NOXO molecules, transports their "messages" directly to the brain's limbic system which controls tobacco cravings.
NOXO Memory Boost
New NOXO Memory Boost balm, when applied topically, under the nostrils helps send an intense trigger for distinct and correlated past memories by delivering scent molecules into the brain's olfactory nerves. NOXO Memory Boost balm utilizes the new science of olfaction to detoxify and oxygenate the body. Research has been found that this process can help stimulate the olfactory receptors and therefore enhance one’s ability to perceive and improve memory recall.
NOXO Sweets Control
New NOXO Sweets Control balm, when applied topically, under the nostrils, desensitizes one’s desire to consume sweet foods. The craving to eat becomes diminished, triggering a positive, mood-enhancing benefit in the brain, which actually suppresses the desire to eat. Independent trials indicated that by using NOXO Sweets Control, individuals lost weight and stopped wanting sweet foods - particularly chocolate - within three weeks.
Tests showed that when the olfactory senses were saturated with NOXO Sweets Control, individuals no longer craved sweet foods. Once the appetite for sweet foods is diminished, the brain registers a decrease in the desire for very sweet tastes and dieting becomes easy. Test individuals did cut their consumption of sweet foods and did not increase their intake of fatty foods to compensate.
NOXO Anxiety Relief
New NOXO Anxiety Relief balm reduces anxiety associated with panic attacks, shortness of breath, dizziness, hot flashes and/or chills. NOXO Anxiety Relief balm reduces the startle reaction; also called the startle response, startle reflex or alarm reaction, which is the response of mind and body to a sudden unexpected stimulus, such as a flash of light, or a loud noise. NOXO Anxiety Relief also has calming effects due to the molecular properties of its ingredients. In addition NOXO Anxiety Relief reduces stress and anxiety in cancer patients undergoing Magnetic Resonance Imaging by a massive 63 percent.
NOXO Mood Lifter
New NOXO Mood Lifter makes you feel your best in a Calm-Energy State. A mood is a relatively long lasting emotional state and is a product of two dimensions: energy and tension. A person can be energetic or tired while also being tense or calm. People feel best when they are in a calm-energy mood and the components of NOXO Mood Lifter balm enables the body to feel this fundamental mood connection. Where there is a food-mood connection, NOXO Mood Lifter balm decreases the desire for food and enables the calm-energy state to exist.
NOXO Appetite Control
New NOXO Appetite Control Improves Weight Loss And Weight Maintenance. Smelling food can trigger instinctive or mindless behavior and we therefore put food in our mouth. An emotional state could also trigger a desire for food. NOXO Appetite Control replaces these triggers and gives us control while replacing the need to eat the donut with the pleasure of feeling comfortable, at home, and secure at work. NOXO Appetite Control balm helps control appetite and all those irrational responses we have to food. NOXO Appetite Control balm used consciously gives us control of cravings where our own will power might fail.
NOXO Nausea Relief
New NOXO Nausea Relief Is Effective In Reducing Nausea, Vomiting, Headache and Migraine. Both physiological and psychological problems can cause nausea. Not only are disgusting smells, bad digestion, tonsillitis, flu, migraine, hangover or food poisoning a reason for nausea, but allergies, motion sickness and early pregnancy can also be a factor. NOXO Nausea Relief balm may also be used as a headache or migraine remedy. That means you get natural headache relief just as potent as popping a couple of 500-milligram Tylenols, but without any long-term side effects or buildup of tolerance levels. And Tylenol doesn’t ease tension and relax your muscles like NOXO Nausea Relief balm can.
NOXO Stress Relief
New NOXO Stress Relief Is Effective In Relaxing Brain Waves And Reducing Stress And Toxins Stress is the term used to describe any reaction to a physical, mental or emotional stimulus that upsets the body's natural balance. Stress causes the entire body to malfunction, creating imbalances in all the systems of the body, resulting in obesity, exhaustion, digestive disorders, circulatory disorders and depression. Whether stress is related to work or family life, most of us experience too much stress in our daily life. Directions include keeping a stress diary for one week to identify what triggers stress in you. Taking NOXO at these trigger points can be a major step controlling and reducing harmful stress and the resulting toxins.
NOXO Menopausal Support
New NOXO Menopausal Support contains A blend of molecular ingredients to help lift your spirits and provide balance during your transition. This balm is to be applied to the ends of your nostrils so that you can inhale the scent deeply three times as needed.
E-mail: support@noxoinfo.com
Dr. Pinney worked with the Department of Justice to commercialize this product in order to support the brave efforts of our military, first responders, and law enforcement personnel. The earlier, first-generation product has been used extensively around the world including NYFD and first responders after 9/11, Dover AFB, and after natural disasters resulting from tsunamis, earthquakes, and hurricanes. This technology and the new second-generation products have now found its way into the medical and dental arena.
Olfaction refers to the sense of smell. Specialized sensory cells of the nasal cavity mediate this sense. For humans, the olfactory system detects volatile chemicals. The chemicals themselves, which activate the olfactory system, generally at very low concentrations, are called odors. Humans respond to chemical stimuli in their environments through chemoreception processes. Chemoreception depends primarily on the senses of taste, smell and includes trigeminal nerve stimulation in the nasal area. Chemoreception relies on chemicals that act as signals to regulate cell function, without the chemical necessarily being taken into the cell for metabolic purposes. While many chemicals, hormones and neurotransmitters, occur within organisms and serve to regulate specific physiological activities, chemicals in the external environment are also perceived by and elicit responses. The company intends to complete the development of new products so that human behaviors can be modified by selectively inhibiting or changing chemo-perception or by causing a selected chemo-perceptions take place.
The company announced its new research facility. The research efforts conduct their focus on monetizable olfactory perception altering technologies. The NOXO Olfactory Research Laboratory is developing new and advanced products for the company, which may have a material effect on human biological functions and neurological systems responses.
HOW NOXO PRODUCTS WORK - THE SCIENCE OF NOXO
There are 12 “Major” terminal nerves in the body, all but one terminate in the brain stem. The one that doesn’t is the olfactory nerve that terminates just below the the frontal lobe on the bottom side of the brain near both the brain interior and tangential to the lower frontal cortex (the frontal cortex being the major cognitive center of the brain). See diagram. The olfactory bulb is in red:
No one really knows why this nerve terminates here and not where the other 11 nerves do. However because it is where it’s located, it has access to several other areas including the limbic system which is the emotional center of the brain.
From its location, the olfactory bulb receives input from the olfactory nerves and transmits smell information from the nose to the brain. By observing it “work” under an fMRI, we’ve learned that this center not only transmits data to the brain but specifically receives it from other “interior” brain areas such as the hippocampus and amygdala as well as from our “thinking” neocortex. With this in mind, the center receives both emotional and thinking messages.
Summing it up its functions appear to be that of “enhancing discrimination between different smells” as well as filtering out many odors to permit the transmission of specific ones. The fact that it permits the “cognitive or thinking” brain areas to participate, even to modify the detection and discrimination of odors is what makes NOXO's work, operable.
The Olfactory Bulb is only part of the entire Olfactory or smell system as you can see in the diagram below:
Nerve cell extensions (axons) from the olfactory system converge in the bulb where other cells (mitral cells) send their axons or extensions of themselves into a number of brain areas including the medial amygdala and the entorhinal cortex.
Within the central nervous system, odors are seen as “patterns of neuronal activity” and may be encoded by other sensory areas including the area of the brain responsible for interpreting sound patterns. Notice how close for example the highly cognitive prefrontal cortex is to the olfactory bulbs. On an fMRI, it is obvious that they communicate. Also notice how close the Temporal Lobes (areas in green) are to the olfactory system. The Temporal Cortex (working in conjunction with the limbic system [emotional center]) is responsible for the formation of our memories.
Below is a diagram of the Brain’s Listening/Hearing Center. Notice it’s proximity to the Temporal lobes and that it lies adjacent to the brain’s interior limbic system:
MUSIC, unlike any other stimulus is a whole brain activity. When you or I listen to music, every single part of our brain picks up the stimulus and engages in its processing.
THEREFORE, even the brains olfactory system is involved in music processing.
Because our smell center is “set” off by itself near the emotional and thinking centers of the brain, smells can generate memories and specifically “memories of sounds.” FOR EXAMPLE: a thought of Sunday Morning breakfasts cooked by our grandmother conjures up images of tastes (for me biscuits and redeye gravy, etc.); visuals (my grandmother baking) and sounds (specifically music that she would have on the radio, usually religious songs from Sunday services.
That NOXO uses memories of sounds (which is really what we are talking about) to engage the brain’s other systems is not all that surprising. NOXO knows that its’ our brain’s listening system that processes sound, but we refer to the thinking part of the brain (the cerebral cortex) a perceiving and processing our “musical” sounds.
Admittedly, one must know a great deal about the brain to understand what NOXO science is talking about and physicians do tend not to understand this area as well as neuroscientists.
When NOXO talks about “tricking” the cortical areas, it's true. The smells are being processed, but it’s the other brain areas that are being bamboozled into perceiving something other than what is real.
So this is what we focus on when doing research relating to present and future products.
NOXO Odor InhibitorNew NOXO Odor Inhibitor balm, secret proprietary product formula of 14 special ingredients which blocks nauseating and offensive odors when applied topically, under the nostrils.
NOXO Smoking ControlNew NOXO Smoking Control balm, when applied topically, under the nostrils reduces an abstaining tobacco user's urge to smoke. The scent of NOXO molecules, transports their "messages" directly to the brain's limbic system which controls tobacco cravings.
NOXO Memory BoostNew NOXO Memory Boost balm, when applied topically, under the nostrils helps send an intense trigger for distinct and correlated past memories by delivering scent molecules into the brain's olfactory nerves. NOXO Memory Boost balm utilizes the new science of olfaction to detoxify and oxygenate the body. Research has been found that this process can help stimulate the olfactory receptors and therefore enhance one’s ability to perceive and improve memory recall.
NOXO Sweets ControlNew NOXO Sweets Control balm, when applied topically, under the nostrils, desensitizes one’s desire to consume sweet foods. The craving to eat becomes diminished, triggering a positive, mood-enhancing benefit in the brain, which actually suppresses the desire to eat. Independent trials indicated that by using NOXO Sweets Control, individuals lost weight and stopped wanting sweet foods - particularly chocolate - within three weeks.
Tests showed that when the olfactory senses were saturated with NOXO Sweets Control, individuals no longer craved sweet foods. Once the appetite for sweet foods is diminished, the brain registers a decrease in the desire for very sweet tastes and dieting becomes easy. Test individuals did cut their consumption of sweet foods and did not increase their intake of fatty foods to compensate.
NOXO Anxiety Relief New NOXO Anxiety Relief balm reduces anxiety associated with panic attacks, shortness of breath, dizziness, hot flashes and/or chills. NOXO Anxiety Relief balm reduces the startle reaction; also called the startle response, startle reflex or alarm reaction, which is the response of mind and body to a sudden unexpected stimulus, such as a flash of light, or a loud noise. NOXO Anxiety Relief also has calming effects due to the molecular properties of its ingredients. In addition NOXO Anxiety Relief reduces stress and anxiety in cancer patients undergoing Magnetic Resonance Imaging by a massive 63 percent.
NOXO Mood LifterNew NOXO Mood Lifter makes you feel your best in a Calm-Energy State. A mood is a relatively long lasting emotional state and is a product of two dimensions: energy and tension. A person can be energetic or tired while also being tense or calm. People feel best when they are in a calm-energy mood and the components of NOXO Mood Lifter balm enables the body to feel this fundamental mood connection. Where there is a food-mood connection, NOXO Mood Lifter balm decreases the desire for food and enables the calm-energy state to exist.
NOXO Appetite ControlNew NOXO Appetite Control Improves Weight Loss And Weight Maintenance. Smelling food can trigger instinctive or mindless behavior and we therefore put food in our mouth. An emotional state could also trigger a desire for food. NOXO Appetite Control replaces these triggers and gives us control while replacing the need to eat the donut with the pleasure of feeling comfortable, at home, and secure at work. NOXO Appetite Control balm helps control appetite and all those irrational responses we have to food. NOXO Appetite Control balm used consciously gives us control of cravings where our own will power might fail.
NOXO Nausea Relief New NOXO Nausea Relief Is Effective In Reducing Nausea, Vomiting, Headache and Migraine. Both physiological and psychological problems can cause nausea. Not only are disgusting smells, bad digestion, tonsillitis, flu, migraine, hangover or food poisoning a reason for nausea, but allergies, motion sickness and early pregnancy can also be a factor. NOXO Nausea Relief balm may also be used as a headache or migraine remedy. That means you get natural headache relief just as potent as popping a couple of 500-milligram Tylenols, but without any long-term side effects or buildup of tolerance levels. And Tylenol doesn’t ease tension and relax your muscles like NOXO Nausea Relief balm can.
NOXO Stress Relief New NOXO Stress Relief Is Effective In Relaxing Brain Waves And Reducing Stress And Toxins Stress is the term used to describe any reaction to a physical, mental or emotional stimulus that upsets the body's natural balance. Stress causes the entire body to malfunction, creating imbalances in all the systems of the body, resulting in obesity, exhaustion, digestive disorders, circulatory disorders and depression. Whether stress is related to work or family life, most of us experience too much stress in our daily life. Directions include keeping a stress diary for one week to identify what triggers stress in you. Taking NOXO at these trigger points can be a major step controlling and reducing harmful stress and the resulting toxins.
NOXO Menopausal SupportNew NOXO Menopausal Support contains A blend of molecular ingredients to help lift your spirits and provide balance during your transition. This balm is to be applied to the ends of your nostrils so that you can inhale the scent deeply three times as needed.
E-mail: support@noxoinfo.com